BPC-157 and TB-500 – two best peptides for post-injury regeneration
Injuries and accidents can happen during any type of physical activity. Whether we train in competitive sports or recreationally, minor overloads can occur. The sports supplementation market offers us many joint products that are supposed to support faster recovery and help us get back on our feet more quickly. One of the recommended combinations is the peptides TB-500 and BPC-157. In this article, we will examine the action of both peptides, consider their impact on preventing overloads, and see how they perform in case of injuries. We will also answer the question of whether it is worth using them.
What is BPC-157 and TB-500?
For those who are new to peptides, these names may sound quite mysterious and reminiscent of characters from the Terminator movie, such as T-800 (Arnold) and his opponent T-1000. While there is a similarity in naming, their actions on the human body are completely different. Peptides are meant to support our bodies to stay healthy and strong, while the Terminator was supposed to eliminate the human species. Returning to the point.
BPC-157 peptide is short for Body Protective Compound 157. It consists of 15 amino acids and was first isolated in the 1990s. The main purpose of using BPC-157 is to support wound healing, including reducing inflammation. BPC peptide also stimulates the formation of new collagen fibers and maintains the properties of existing ones, which makes it widely used as joint support.
TB-500 product is a synthetic protein fragment composed of 44 amino acids. Its full name is Thymosin Beta-4. Like BPC, TB-500 was isolated in the 1990s and has been used for body regeneration. The mechanism of action of the peptide is quite simple, as it stimulates the growth of beta-thymosin hormone. It affects the initiation of many regenerative processes that support the body systemically.
What are the benefits of using BPC-157 and TB-500 peptides during injuries?
Now that we know what is hidden behind these mysterious acronyms, let’s take a closer look at how these peptides work on the body.
- Improves tissue healing — Both TB-500 and BPC-157 significantly accelerate tissue healing. This means that both compounds can be used to shorten the recovery time during injuries. This effect can also be useful when recovering from surgery, where our skin requires rebuilding and scar tissue formation.
- Regenerates joints, tendons, ligaments, and muscles. Since BPC stimulates collagen production, we can experience a faster return to full strength after an injury. Many bodybuilders also use TB-500 and BPC as muscle recovery support.
- Reduces inflammation — both peptides will reduce inflammation in the body.
- Prevents injuries — the action of BPC-157 and TB-500 effectively counteracts overuse injuries that can lead to tissue damage.
- Improves blood flow and nutrient delivery — this action is also of interest to those training at the gym.
Peptides and joint and bone regeneration
Special attention should be paid to the effect of BPC-157 and TB-500 on joints and bones. Why? Many people use peptides for this purpose, especially during the recovery period after an injury. As research shows, the use of BPC-157 can even double the time of healing of a broken bone compared to not using the peptide [1]. Furthermore, BPC accelerates the regeneration of a damaged Achilles tendon by intensifying the production of cells responsible for the formation of connective tissue [2]. By using peptides, we have the opportunity to start the repair processes more quickly. Peptides can be compared to good insurance. We don’t need to search for help; our body starts the repair process much faster.
TB-500 and BPC-157 similarities and differences
If we talk about similarities, both peptides are excellent when it comes to regeneration. Both BPC-157 and TB-500 will support all processes of damaged tissue repair. They will be responsible for the use of the body’s stem cells, where needed at a given moment. Similarly, TB and BPC will be an effective solution in the treatment of joint injuries.
In the case of differences, TB-500 works systemically on the entire body, while BPC-157 is best suited to the site of the injury. This means that it doesn’t matter how and where we administer TB, while BPC is best applied to the area where we are dealing with an injury. For example, if we have a problem with tennis elbow, we can administer TB subcutaneously in the abdomen, while BPC subcutaneously in the area of the wrist extensor attachments. In addition, BPC affects all kinds of problems related to inflammation, not just modulating the immune system. An example is BPC in capsules, which can be used as support for the digestive system [3]. The third significant difference is the duration of action. As scientific publications indicate, BPC may show faster therapeutic action than Thymosin Beta-4.
What other effects do TB500 and BPC-157 show?
- They protect the nervous system — both compounds effectively protect the nervous system from neurodegenerative diseases.
- Improve digestion — BPC-157 improves digestion and the absorption of nutrients. The oral version of the peptide is particularly recommended.
- Treat heart and vascular diseases — peptides have a protective effect on the heart and the circulatory system [4].
- Improve strength and endurance – peptides can cause an increase in the number of red blood cells, which will translate into more efficient oxygen transport. More oxygen in the muscles is an opportunity for them to work more efficiently.
How to use TB-500 and BPC-157 peptides?
When combining both peptides, we can use a dose of 250 mcg of BPC-157 administered twice a day in the area of the injury. TB, on the other hand, in an amount of 2 mg administered every 5 days. There is no need to use Thymosin Beta-4 every day. In the case of very severe injuries or postoperative joints, it is worth using a dose of even 1 mg daily! This is a fairly large amount, but this action can significantly accelerate the recovery time. For those who live for sports and through sports, every day counts.
What to remember when using BPC-157 and TB-500?
- Peptides are aimed at supporting the regeneration of damaged tissues.
- Their action intensifies repair processes and limits inflammation.
- The use of peptides is safe and does not cause side effects.
Source:
1. https://pubmed.ncbi.nlm.nih.gov/10071911/
2. https://pubmed.ncbi.nlm.nih.gov/14554208/
3. https://pubmed.ncbi.nlm.nih.gov/29998800/
4. https://pubmed.ncbi.nlm.nih.gov/20536454/